Our service

To provide biological high-end technical services for scientific workers in the field of basic research

Conventional Yeast Platform

Nanobody Platform

AI Screening Protein-Interactins

Peptide Library Screening

Technology

Peptides are synthetically accessible, amenable to chemical tailoring, and have the potential to bind the typically shallow surfaces seen in therapeutically relevant—and historically intractable—protein–protein interactions (PPIs). Peptides can either act as natural ligands in the form of cofactors, coenzymes, and hormones, or directly interact with macromolecules including proteins, RNA, or DNA.

A major advantage of peptides compared with their small-molecule counterparts is their ability to span and therefore inhibit large binding interfaces.

Peptide library screening as a tool to derive potent therapeutics: current approaches & future strategies Editorial have also been developed for screening libraries of stapled peptides, which are also known to often have improved proteolytic stability and cell penetration over their linear counterparts. For example, peptide screening technologies have brought us a range of potent inhibitors. Peptide-based vaccines have emerged as a powerful approach to counter infectious diseases and cancer.

Ultra-large chemical libraries for the discovery of high-affinity peptide binders, 2020.

Peptide library screening as a tool to derive potent therapeutics: current approaches and future strategies, 2020.

PDAUG: a Galaxy based toolset for peptide library analysis, visualization, and machine learning modeling, 2022.

Peptides for specific intracellular delivery and targeting of nanoparticles: implications for developing nanoparticle-mediated drug delivery, 2010.

Service process

Service content	Working days
1. Gene synthesis (Codon Optimization) /Vector Construction	15d
2. Self-activation of bait plasmid	10 d
3. Co-transfer Bait plasmid and library plasmid 4. Selective medium for yeast screening 5. Sanger sequence of screening results	15 d
6. Verify by Rotation 7. Temporary Data Report	5 d
8. Next-generation sequencing 9. Complete Project Data Report	10 d
Total	55 d

Features

1. Synthetic Library, No Species Limited;

A random peptide library of 6 Amino Acids, with 18 bases of random insertion sites; the library capacity can reach 10^8 cfu.

2. Deliver Time: 55 working days;

3. Comparable accuracy but Lower Cost (compared with phage library screening)

4. Saving 3-4 labor costs;

Services Workflow

Online Consultation

Solution Matching

Service Contract

One-Stop-Services

Project Report

Any question? Get in touch with us!